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肾移植受者中的念珠菌感染:白色念珠菌血清型和血清抗体

Candida contamination in renal transplant recipients: Candida albicans serotypes and sera-antibodies.

作者信息

Ghezzi M C, Trancassini M, Cipriani P, Mancini C, Alfani D, Pretagostini R, Brenciaglia M I

出版信息

G Batteriol Virol Immunol. 1984 Jan-Jun;77(1-6):3-8.

PMID:6399272
Abstract

Candida spp. is an important parasite for the immunocompromised host, and transplant recipients are at high risk for invasive and potentially lethal infections caused by this microorganism. The frequency of colonization at one or more sites and the correlation with humoral antibodies in renal transplant recipients have been studied. Candida strains were identified by cultural and biochemical tests, and moreover serological types of C. albicans were detected. Sera antibodies have been also determined by agglutination and immunodiffusion tests. Our results indicate that about 48.8% of patients had Candida spp. at one or more sites and these yeasts may be of different species or serotypes. None of the patients has had systemic candidiasis and none of them showed any convincing clinical or pathological evidence of invasive Candida disease.

摘要

念珠菌属是免疫功能低下宿主的重要寄生虫,移植受者面临由这种微生物引起的侵袭性和潜在致命感染的高风险。已经研究了肾移植受者中一个或多个部位的定植频率及其与体液抗体的相关性。通过培养和生化试验鉴定念珠菌菌株,此外还检测了白色念珠菌的血清型。血清抗体也通过凝集和免疫扩散试验测定。我们的结果表明,约48.8%的患者在一个或多个部位存在念珠菌属,这些酵母菌可能属于不同的物种或血清型。所有患者均未发生系统性念珠菌病,也没有任何患者表现出侵袭性念珠菌病的确凿临床或病理证据。

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