干扰素α在人类肿瘤中的研究。

Studies with interferon-alpha in human tumors.

作者信息

Einhorn S, Strander H

出版信息

Med Oncol Tumor Pharmacother. 1984;1(2):97-9. doi: 10.1007/BF02934980.

Abstract

Clinical trials with IFN-alpha, produced from buffy coats of leukocytes, have been going on at Radiumhemmet, Karolinska Hospital since 1969. In some of the benign and malignant tumor diseases studied, IFN has been shown to induce regressions. In the case of the benign tumor juvenile laryngeal papillomatosis, IFN has been shown to be superior to other treatment modalities. So far IFN has not been shown to be superior to conventional treatment in any of the malignant tumors studied.

摘要

自1969年以来，卡罗林斯卡医院镭疗科一直在进行使用从白细胞血沉棕黄层中提取的α干扰素的临床试验。在一些所研究的良性和恶性肿瘤疾病中，干扰素已被证明可诱导肿瘤消退。在良性肿瘤青少年喉乳头状瘤的病例中，干扰素已被证明优于其他治疗方式。到目前为止，在任何所研究的恶性肿瘤中，干扰素尚未被证明优于传统治疗。