Brabant G, Kleine P, Hesch R D, von zur Mühlen A
Ultrasound Med Biol. 1983;Suppl 2:393-6.
Because of the frequent topographically unusual localization of parathyroid tumours the intraoperative identification remains a problem to the surgeon. Therefore, the accuracy of the preoperative localization of the parathyroid glands was assessed in 17 patients with extrarenal hyperparathyroidism using high resolution sonography (Siemens RA 1 and Sonoline 8000 small parts scanner operating at 7.5 mHz/5 MHz). The clinically suspected diagnosis was supported by changes in calcium, phosphate and alkaline phosphatase levels without any signs of renal dysfunction and by elevated levels of PTH in the 44-68 hPTH radioimmunoassay. All patients subsequently underwent surgery and the preoperative sonographic diagnosis could be confirmed in 82% of the cases. The smallest adenoma visualized measured 0.8 X 0.8 cms. The only carcinoma in the study did not appear sonographically different to the adenomata. These preliminary results suggest that high resolution sonography may become a valuable aid in the surgical management of extrarenal hyperparathyroidism.
由于甲状旁腺肿瘤在局部位置上常常不寻常，术中识别对外科医生来说仍是个问题。因此，我们使用高分辨率超声（西门子RA 1和以7.5兆赫兹/5兆赫运行的Sonoline 8000小器官扫描仪）对17例肾外甲状旁腺功能亢进患者甲状旁腺的术前定位准确性进行了评估。临床疑似诊断得到了钙、磷和碱性磷酸酶水平变化（无任何肾功能不全迹象）以及44 - 68小时甲状旁腺激素放射免疫测定中甲状旁腺激素水平升高的支持。所有患者随后均接受了手术，术前超声诊断在82%的病例中得到证实。超声可见的最小腺瘤尺寸为0.8×0.8厘米。该研究中唯一的癌在超声表现上与腺瘤并无差异。这些初步结果表明，高分辨率超声可能会成为肾外甲状旁腺功能亢进外科治疗中的一项有价值的辅助手段。
