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人类分娩的启动。

Initiation of parturition in humans.

作者信息

Drover J W, Casper R F

出版信息

Can Med Assoc J. 1983 Feb 15;128(4):387-92.

Abstract

The mechanism by which parturition is initiated in humans is largely unknown. The placenta and fetal membranes appear to play the major role in the initiation of labour, and the fetus may influence the timing of labour. Clinical observations and experiments with animals have revealed that placental neuropeptides may be able to control steroid metabolism and trigger the onset of labour, while the fetus may be able to interact with such events to initiate parturition at an appropriate time. However, further study is needed to determine the role of placental releasing factors and glycoprotein hormones and their ability to control placental steroid metabolism.

摘要

人类分娩启动的机制在很大程度上尚不清楚。胎盘和胎膜似乎在分娩发动中起主要作用,而胎儿可能影响分娩时间。临床观察和动物实验表明,胎盘神经肽可能能够控制类固醇代谢并引发分娩开始,而胎儿可能能够与这些事件相互作用,在适当的时候启动分娩。然而,需要进一步研究以确定胎盘释放因子和糖蛋白激素的作用及其控制胎盘类固醇代谢的能力。

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本文引用的文献

2
Plasma progesterone in mother and foetus in the second half of human pregnancy.
J Obstet Gynaecol Br Emp. 1962 Oct;69:772-9. doi: 10.1111/j.1471-0528.1962.tb01279.x.
3
Blood progesterone levels in abnormal pregnancies.异常妊娠中的血孕酮水平。
J Obstet Gynaecol Br Emp. 1960 Oct;67:785-91. doi: 10.1111/j.1471-0528.1960.tb10436.x.
4
Gap junction formation and regulation in myometrium.
Am J Physiol. 1980 Nov;239(5):C217-28. doi: 10.1152/ajpcell.1980.239.5.C217.

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