Weizman Z, Schmueli A, Deckelbaum R J
Am J Dis Child. 1983 Mar;137(3):253-5.
Eighteen infants with severe prolonged diarrhea were fed successfully by continuous drip enteral feedings with an elemental diet. The mean weight gain was 6.4 +/- 0.7 g/kg/day, using a solution containing up to 87 kcal/dL at volumes up to 260 mL/kg/day. No cardiovascular or metabolic abnormalities occurred. Advantages of the continuous drip regimen were demonstrated by an adaptation phase with a plateau or even a decline in body weight in 12 patients, with weaning from continuous periodic feedings without changing the total caloric or volume intake. Continuous drip feeding provides an alternative for total parenteral nutrition in patients with severe prolonged diarrhea and intolerance to even an elemental diet given as periodic feedings.
18例严重迁延性腹泻婴儿通过持续滴注要素饮食进行肠内喂养获得成功。使用能量高达87千卡/分升、每日量达260毫升/千克的溶液时,平均体重增加为6.4±0.7克/千克/日。未出现心血管或代谢异常。12例患者在适应期出现体重平台期甚至下降,随后在不改变总热量或摄入量的情况下从持续定时喂养过渡到持续滴注喂养,这证明了持续滴注方案的优势。持续滴注喂养为严重迁延性腹泻且对即使是定时喂养的要素饮食也不耐受的患者提供了全胃肠外营养的替代方法。