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肾上腺髓质切除术联合化学性交感神经切除术对大鼠冷诱导下内分泌胰腺反应的影响。

Effects of adrenal demedullation combined with chemical sympathectomy on cold-induced responses of endocrine pancreas in rats.

作者信息

Habara Y, Ohno T, Yahata T, Kuroshima A

出版信息

Experientia. 1983 Apr 15;39(4):399-400. doi: 10.1007/BF01963145.

Abstract

Adrenal demedullation combined with chemical sympathectomy with 6-hydroxydopamine (ACS) lowered plasma glucagon and insulin levels in rats. Acute cold exposure increased plasma glucagon in both ACS and control rats, while it increased plasma insulin only in ACS rats. ACS rats responded to cold with a smaller increase in plasma glycerol and a more pronounced elevation of plasma free fatty acids.

摘要

肾上腺去髓质术联合6-羟基多巴胺化学性交感神经切除术(ACS)可降低大鼠血浆胰高血糖素和胰岛素水平。急性冷暴露使ACS大鼠和对照大鼠的血浆胰高血糖素均升高,而仅使ACS大鼠的血浆胰岛素升高。ACS大鼠对寒冷的反应是血浆甘油增加较少,而血浆游离脂肪酸升高更为明显。

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