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雄性狨猴(Callithrix jacchus jacchus)对人绒毛膜促性腺激素刺激的血浆睾酮反应。

Plasma testosterone response to hCG stimulation in the male marmoset monkey (Callithrix jacchus jacchus).

作者信息

Kholkute S D, Aitken R J, Lunn S F

出版信息

J Reprod Fertil. 1983 Mar;67(2):457-63. doi: 10.1530/jrf.0.0670457.

Abstract

In adult animals the intramuscular injection of hCG was followed by a rapid rise in plasma testosterone levels within 2-3 h and at doses of 40 and 80 i.u. hCG this primary response was followed by a second peak of testosterone at 48 h. Prepubertal marmosets also responded to hCG stimulation with a rapid increase in plasma testosterone levels within 3 h, but the magnitude of this peak was lower than that observed in adult animals and no biphasic pattern was observed. In adult and prepubertal animals a second dose of hCG (40 i.u.) administered 24 h after the initial injection failed to produce a further rapid increment in plasma testosterone levels.

摘要

在成年动物中,肌肉注射人绒毛膜促性腺激素(hCG)后,血浆睾酮水平在2 - 3小时内迅速上升,当hCG剂量为40和80国际单位时,这一初始反应之后在48小时出现第二个睾酮峰值。青春期前的狨猴对hCG刺激也有反应,血浆睾酮水平在3小时内迅速升高,但该峰值的幅度低于成年动物,且未观察到双相模式。在成年和青春期前动物中,在首次注射后24小时给予第二剂hCG(40国际单位)未能使血浆睾酮水平进一步快速升高。

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