Petty B G, Sowa D T, Charache P
JAMA. 1983 Apr 15;249(15):2069-72.
A bacteriology technologist was found to have acute polyarticular arthritis after a brief prodromal illness. Gram's stain of fluid from the right knee showed pleomorphic gram-negative organisms, while that of fluid from the right elbow and left wrist showed gram-negative cocci and diplococci. Culture of fluid from the right knee yielded Salmonella enteritidis. Cultures of fluid from all other joints, collected after starting therapy, were negative. An enzyme-linked immunosorbent assay of fluid from the right elbow confirmed Neisseria meningitidis, group C. This organism was also isolated from the patient's throat. This case represents concurrent infection of separate joints by two bacterial pathogens, one confirmed by culture and one by current immunodiagnostic techniques.
一名细菌学技术人员在经历短暂的前驱疾病后，被发现患有急性多关节关节炎。右膝关节积液的革兰氏染色显示多形性革兰氏阴性菌，而右肘和左手腕关节积液的革兰氏染色显示革兰氏阴性球菌和双球菌。右膝关节积液培养出肠炎沙门氏菌。开始治疗后采集的所有其他关节积液培养均为阴性。右肘关节积液的酶联免疫吸附测定证实为C群脑膜炎奈瑟菌。该菌也从患者咽喉部分离出来。此病例代表了两个关节同时被两种细菌病原体感染，一种通过培养确诊，另一种通过当前免疫诊断技术确诊。
