Newland J R, Linke R P, Kleinsasser O, Lennert K
Virchows Arch A Pathol Anat Histopathol. 1983;399(2):233-6. doi: 10.1007/BF00619583.
A case of a patient presenting with supraclavicular and cervical lymph node enlargement with demonstration of amyloid is presented. Histologic features are described. Amyloid deposition was not found in any other organ. Immunohistochemical typing with antisera raised against protein AA, A lambda, and A kappa showed a reaction only against A lambda. Thus, this case belongs to the immunoglobulin lambda light chain-derived types that occur in many other parts of the body, particularly the respiratory tract.
本文报告了一例表现为锁骨上和颈部淋巴结肿大且证实存在淀粉样蛋白的患者病例。描述了其组织学特征。在其他任何器官均未发现淀粉样蛋白沉积。使用针对蛋白AA、Aλ和Aκ的抗血清进行免疫组织化学分型,结果显示仅与Aλ有反应。因此,该病例属于免疫球蛋白λ轻链衍生类型,这种类型见于身体的许多其他部位,尤其是呼吸道。