Hendrikx W M
Z Parasitenkd. 1983;69(1):119-26. doi: 10.1007/BF00934016.
The oral, percutaneous and subcutaneous routes of infection of Oswaldocruzia filiformis were investigated in amphibia. Tadpoles of Bufo bufo and Rana temporaria can be infected with O. filiformis when kept temporarily in a suspension of infective larvae in water. Larval stages and subadults were found in tadpoles. All stages of the parasite, including egg-producing females, were found after metamorphosis of the host. However, under natural circumstances infection of tadpoles seems unlikely. Oral infections in metamorphosed hosts of both species were successful in 97.5% of the host animals used. The first eggs appeared 29 days after infection in the faeces. The oral route seems to be normal for O. filiformis in amphibia. Experiments on percutaneous infections did not reveal actual penetration of larvae in or through the skin nor a subsequent migration through host tissues. Sometimes a few larvae were found in the stomach and intestine, but in these particular cases the experimental conditions did not totally exclude the possibility of oral infections. Consequently, the percutaneous route of infection is not plausible for O. filiformis. Subcutaneous inoculation of infective larvae seems to be a possible way of establishing experimental infections. Erratic localisation of the parasite in the enlarged gall bladder of the host was observed.
在两栖动物中研究了丝状奥斯瓦尔德线虫的经口、经皮和皮下感染途径。将蟾蜍和欧洲林蛙的蝌蚪暂时饲养在含有感染性幼虫的水中时，它们会被丝状奥斯瓦尔德线虫感染。在蝌蚪体内发现了幼虫阶段和亚成虫。在宿主变态后发现了寄生虫的所有阶段，包括产卵雌虫。然而，在自然情况下，蝌蚪被感染的可能性似乎不大。在两种变态宿主中，经口感染在97.5%的实验动物中成功。感染后29天，粪便中出现了第一批虫卵。经口途径似乎是丝状奥斯瓦尔德线虫在两栖动物中的正常感染途径。经皮感染实验未发现幼虫实际穿透皮肤或通过皮肤，也未发现随后在宿主组织中的迁移。有时在胃和肠道中发现少量幼虫，但在这些特殊情况下，实验条件并未完全排除经口感染的可能性。因此，丝状奥斯瓦尔德线虫经皮感染途径不太可能。皮下接种感染性幼虫似乎是建立实验性感染的一种可能方法。观察到寄生虫在宿主肿大胆囊中的定位不稳定。
