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血友病患者的骨科手术

Orthopaedic surgery in hemophilic patients.

作者信息

Willert H G, Horrig C, Ewald W, Scharrer I

出版信息

Arch Orthop Trauma Surg (1978). 1983;101(2):121-32. doi: 10.1007/BF00433272.

Abstract

Since 1970 we performed 18 operations in hemophilic patients: 7 synovectomies, 2 elongations of the achilles-tendon, 1 hip arthrodesis, 2 endoprosthetic replacements of the hip, 2 intertrochanteric flexion- and varus-osteotomies, 1 excision of a pseudo-tumor and 2 removals of hematomas of the knee joint. The synovectomies were done only in joints affected by frequent hemorrhages. The bleeding frequency could be reduced considerably and the range of motion could be improved. The indication for several other orthopaedic procedures depended on the orthopaedic symptoms. The results were satisfactory without major complications during the healing period. During surgery and the following postoperative care the antihemophilic factor was substituted up to levels between 60 and 120%. The factor VIII or IX was controlled daily and Hb, GOT, GPT and the Australia antigen-antibody on a weekly base. The length of the substitution regimen was dependent on the individual wound healing and the postoperative treatment.

摘要

自1970年以来,我们对血友病患者实施了18例手术:7例滑膜切除术、2例跟腱延长术、1例髋关节融合术、2例髋关节假体置换术、2例转子间屈曲和内翻截骨术、1例假肿瘤切除术以及2例膝关节血肿清除术。滑膜切除术仅针对频繁出血的关节进行。出血频率可大幅降低,关节活动范围也得以改善。其他几种骨科手术的指征取决于骨科症状。结果令人满意,愈合期无重大并发症。手术期间及术后护理过程中,抗血友病因子替代至60%至120%之间的水平。每日监测因子VIII或IX,每周监测血红蛋白、谷草转氨酶、谷丙转氨酶及澳大利亚抗原抗体。替代方案的时长取决于个体伤口愈合情况及术后治疗。

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