α链病中的非典型浆细胞。

Atypical plasma cells in alpha-chain disease.

作者信息

Veloso F T, Saleiro J V, Oliveira A O, de Freitas A F

出版信息

Cancer. 1983 Jul 1;52(1):79-82. doi: 10.1002/1097-0142(19830701)52:1<79::aid-cncr2820520116>3.0.co;2-w.

DOI:10.1002/1097-0142(19830701)52:1<79::aid-cncr2820520116>3.0.co;2-w

Abstract

Pathologic features of the jejunal mucosa of a patient with alpha-chain disease in its early transition to malignant stage, are described. Ultrastructural alterations were seen in some plasma cell, close similar to those described in myeloma plasma cells. Ultrastructural studies of biopsy specimens in alpha-chain disease, may permit recognition of its early transition to malignant stage and thereby encourage earlier use of cytotoxic drugs.

摘要

描述了一名α链病患者空肠黏膜在早期向恶性阶段转变时的病理特征。在一些浆细胞中观察到超微结构改变，与骨髓瘤浆细胞中描述的改变非常相似。对α链病活检标本进行超微结构研究，可能有助于识别其向恶性阶段的早期转变，从而鼓励更早使用细胞毒性药物。