Cooper B R, Howard J L, Soroko F E
J Clin Psychiatry. 1983 May;44(5 Pt 2):63-6.
The discovery of bupropion's potential antidepressant activity resulted from studies of its behavioral effects in a number of animal models of depression. These animal models and data pertaining to their selectivity for other standard antidepressant drugs are reviewed.
安非他酮潜在抗抑郁活性的发现源于对其在多种抑郁症动物模型中行为效应的研究。本文综述了这些动物模型以及与其对其他标准抗抑郁药物选择性相关的数据。