通过向去势雌性和雄性大鼠胃内插管给予7,12-二甲基苯并(a)蒽诱导的包皮肿瘤。
Preputial tumors induced by intragastric intubations of 7,12-dimethylbenz(a)anthracene in gonadectomized female and male rats.
作者信息
Yoshida H
出版信息
J Cancer Res Clin Oncol. 1983;105(3):299-302. doi: 10.1007/BF00395762.
PMID:6406514
Abstract
A series of administrations of 7,12-dimethylbenz(a)anthracene given at biweekly intervals by gastric intubation to gonadectomized rats of the Sprague-Dawley strain elicited a considerable number of preputial tumors. The tumors commonly consisted of solid and cystic parts with a wide variety of histologic features and were classified as adenomas, carcinomas, and malignant mixed tumors.
摘要
通过胃插管以两周一次的间隔给斯普拉格-道利品系的去性腺大鼠一系列注射7,12-二甲基苯并(a)蒽，引发了大量的包皮肿瘤。这些肿瘤通常由实性和囊性部分组成，具有多种组织学特征，被分类为腺瘤、癌和恶性混合瘤。
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