Baraitser M
Arch Dis Child. 1983 Jun;58(6):404-5. doi: 10.1136/adc.58.6.404.
The approximately tenfold increase in risk (1 in 250 to 1 in 25) to those who have a positive but not extensive family history of recurrent seizures would seem to be considerable but the actual figure of 4% is small. Only if the family history concerns at least 2 closely related members does the risk reach the 10% mark (on the borderline between high and low), but even then the burden of the disorder and response to treatment in the other family members should be taken into account. Familial epilepsy often responds more readily to therapy than other types.
对于有复发性癫痫发作阳性但不广泛家族史的人来说,风险增加约十倍(从250分之一增至25分之一),这似乎相当可观,但实际4%的数字却很小。只有当家族史涉及至少两名密切相关成员时,风险才会达到10%(处于高风险和低风险的临界值),但即便如此,也应考虑其他家庭成员的疾病负担和对治疗的反应。家族性癫痫通常比其他类型的癫痫对治疗的反应更迅速。