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去氨加压素对血浆因子 XII 水平的影响。

Effect of DDAVP on plasma level of factor XII.

作者信息

Nenci G G, Berrettini M, De Cunto M, Agnelli G

出版信息

Br J Haematol. 1983 Jul;54(3):489-92. doi: 10.1111/j.1365-2141.1983.tb02124.x.

Abstract

The effect of DDAVP on blood coagulation factors was investigated after its intravenous infusion into normal subjects. A marked increase in factor XII was observed in addition to the expected rise of factor VIII coagulant activity (VIII:C), factor VIII related antigen (VIIIR:Ag) and plasminogen activator, DDAVP also produced a concomitant but less pronounced rise of factor VII, but there was no change in factors V, IX, X and XI.

摘要

在正常受试者静脉输注去氨加压素后,研究了其对血液凝固因子的影响。除了预期的因子VIII促凝活性(VIII:C)、因子VIII相关抗原(VIIIR:Ag)和纤溶酶原激活剂升高外,还观察到因子XII显著增加。去氨加压素还使因子VII伴随出现但不太明显的升高,但因子V、IX、X和XI没有变化。

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