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去氨加压素对血浆因子 XII 水平的影响。

Effect of DDAVP on plasma level of factor XII.

作者信息

Nenci G G, Berrettini M, De Cunto M, Agnelli G

出版信息

Br J Haematol. 1983 Jul;54(3):489-92. doi: 10.1111/j.1365-2141.1983.tb02124.x.

DOI:10.1111/j.1365-2141.1983.tb02124.x
PMID:6407513
Abstract

The effect of DDAVP on blood coagulation factors was investigated after its intravenous infusion into normal subjects. A marked increase in factor XII was observed in addition to the expected rise of factor VIII coagulant activity (VIII:C), factor VIII related antigen (VIIIR:Ag) and plasminogen activator, DDAVP also produced a concomitant but less pronounced rise of factor VII, but there was no change in factors V, IX, X and XI.

摘要

在正常受试者静脉输注去氨加压素后,研究了其对血液凝固因子的影响。除了预期的因子VIII促凝活性(VIII:C)、因子VIII相关抗原(VIIIR:Ag)和纤溶酶原激活剂升高外,还观察到因子XII显著增加。去氨加压素还使因子VII伴随出现但不太明显的升高,但因子V、IX、X和XI没有变化。

相似文献

1
Effect of DDAVP on plasma level of factor XII.去氨加压素对血浆因子 XII 水平的影响。
Br J Haematol. 1983 Jul;54(3):489-92. doi: 10.1111/j.1365-2141.1983.tb02124.x.
2
Factor VII and fibrinolytic response to deamino-8-D-argenine vasopressin in normal subjects and dissociate response in some patients with haemophilia and von Willebrand's disease.正常受试者中因子 VII 及对去氨基-8-D-精氨酸加压素的纤溶反应,以及血友病和血管性血友病患者中的分离反应。
Br J Haematol. 1980 Jul;45(3):499-511. doi: 10.1111/j.1365-2141.1980.tb07169.x.
3
Properties of the factor VIII after DDAVP (1-deamino-8-D-arginine vasopressin) infusion in normal subjects.正常受试者输注去氨加压素(1-去氨基-8-D-精氨酸加压素)后因子VIII的特性
Tohoku J Exp Med. 1980 Oct;132(2):133-40. doi: 10.1620/tjem.132.133.
4
Reduced effect of exercise and DDAVP on factor VIII-von Willebrand Factor and plasminogen activator after sequential application of both the stimuli.在先后施加运动和去氨加压素这两种刺激后,运动和去氨加压素对凝血因子VIII-血管性血友病因子及纤溶酶原激活物的作用减弱。
Thromb Haemost. 1984 Feb 28;51(1):129-30.
5
The role of the spleen in regulating the plasma levels of factor VIII--von Willebrand's factor after DDAVP.去氨加压素后脾脏在调节血浆VIII因子-血管性血友病因子水平中的作用
Blood. 1982 Dec;60(6):1402-6.
6
Is the pro-adhesive activity of plasma von Willebrand factor counteracted by a physiological inhibitor of platelet adhesiveness?血浆血管性血友病因子的促黏附活性是否会被血小板黏附的生理抑制剂所抵消?
Clin Sci (Lond). 1982 Feb;62(2):239-42. doi: 10.1042/cs0620239.
7
The effect of desamino-D-arginine vasopressin (DDAVP) and naloxone infusions on factor VIII and possible endothelial cell (EC) related activities.去氨基-D-精氨酸血管加压素(DDAVP)和纳洛酮输注对凝血因子VIII及可能的内皮细胞相关活性的影响。
Br J Haematol. 1984 Aug;57(4):651-62.
8
Effect of DDAVP on plasma levels of factor VII and XII.去氨加压素对血浆VII因子和XII因子水平的影响。
Br J Haematol. 1984 May;57(1):173-5. doi: 10.1111/j.1365-2141.1984.tb02878.x.
9
High levels of circulating von Willebrand factor inhibit the release of this protein but not of plasminogen activator after DDAVP.
Thromb Res. 1985 Apr 1;38(1):101-5. doi: 10.1016/0049-3848(85)90011-8.
10
Response of factor VIII/von Willebrand factor to DDAVP in healthy subjects and patients with haemophilia A and von Willebrand's disease.健康受试者、甲型血友病患者及血管性血友病患者中因子VIII/血管性血友病因子对去氨加压素的反应。
Br J Haematol. 1981 Feb;47(2):283-93. doi: 10.1111/j.1365-2141.1981.tb02789.x.

引用本文的文献

1
The subcutaneous administration of the vasopressin analogue 1-desamino-8-D-arginine vasopressin in patients with von Willebrand's disease and hemophilia.对血管性血友病和血友病患者皮下注射血管加压素类似物1-去氨基-8-D-精氨酸血管加压素。
Klin Wochenschr. 1984 Jun 1;62(11):543-8. doi: 10.1007/BF01727749.
2
Reduction of contact activation related fibrinolytic activity in factor XII deficient patients. Further evidence for the role of the contact system in fibrinolysis in vivo.凝血因子XII缺乏患者中接触激活相关纤溶活性的降低。接触系统在体内纤溶作用中作用的进一步证据。
J Clin Invest. 1991 Oct;88(4):1155-60. doi: 10.1172/JCI115416.