Wallace D B, Keil T J
Int J Addict. 1978 Feb;13(2):241-7. doi: 10.3109/10826087809039277.
The core hypothesis deduced from the Dole-Nyswander blockade formulation is that methadone is a sufficient but not necessary condition for abstinence from heroin. It is argued that this hypothesis has not been tested with scientifically adequate research. A research design is suggested. Since the Dole-Nyswander focus is at the physiological and metabolic level, it is argued that the blockade theory, pending, its scientific validation, should be supplemented by sociological, organizational, and economic theory.
从多利-尼斯万德阻断理论推导得出的核心假设是，美沙酮是戒除海洛因的充分但非必要条件。有人认为，这一假设尚未经过科学充分的研究验证。本文提出了一种研究设计。鉴于多利-尼斯万德的研究重点在生理和代谢层面，有人认为，在阻断理论获得科学验证之前，应辅以社会学、组织学和经济学理论。
