Swenson O, Malinin T I
Invest Urol. 1978 Mar;15(5):389-91.
Results of tests on implantable artificial sphincters with a subcutaneous control unit encased in a plastic envelope were previously reported. The plastic deteriorated and in 12 to 18 months caused instrument failure. To obviate this failure, (control) units of titanium alloy with protruding levers were tested in 17 animals for a period of up to 6 months to determine whether fibrosis and tissue ingrowth would hamper the function of the control levers. The device was placed around the urethra distal to the bladder neck. It was set to obstruct the urethra against pressures varying from 40 to 80 cm of water. Erosion of the urethra did not take place. In no instance was the action of the subcutaneous control levers hampered by tissue ingrowth or fibrosis.
先前曾报道过对带有封装在塑料外壳中的皮下控制单元的植入式人工括约肌的测试结果。塑料发生了变质，在12至18个月内导致仪器故障。为避免这种故障，对带有突出杠杆的钛合金（控制）单元在17只动物身上进行了长达6个月的测试，以确定纤维化和组织向内生长是否会妨碍控制杠杆的功能。该装置放置在膀胱颈远端的尿道周围。它被设置为在40至80厘米水柱的不同压力下阻塞尿道。未发生尿道糜烂。在任何情况下，皮下控制杠杆的作用都未受到组织向内生长或纤维化的妨碍。
