Theuring F
Acta Histochem Suppl. 1983;27:317-24.
The power of the physiological regeneration of rat salivary glands has been investigated with 3H-thymidine by means of pulsee, double, and permanent marking as well as the technique of marked mitosis. Animals aged 12 hours up to 24 months were available. The transitory increase of regeneration seen in all the three salivary glands of the bead around the 5th day of life is explained as a consequence of the adaption to extrauterine life. From the second month of life on, the marking index is below 1 p.c. The growth fraction, which was determined by means of frequently repeated puls, and double, marking amounts to approximately 40 p.c. at the age of 19 hours, some 8 p.c. with 6-weeks-olds and as little as 1 or 2 p.c. at the age of 18 months. The determination of the cycle phases by double marking and the marked-mitosis technique revealed the relative constancy of the S, G2, and M-phases. With advancing age, the G1-phase extends. The salivary glands of the head can be classified as stable tissues according to the autoradiographic results.
利用³H-胸腺嘧啶核苷，通过脉冲标记、双重标记、永久性标记以及标记有丝分裂技术，对大鼠唾液腺的生理再生能力进行了研究。选用了年龄从12小时到24个月的动物。出生后第5天左右，在幼鼠所有三个唾液腺中观察到的再生短暂增加现象，被解释为是适应宫外生活的结果。从出生后第二个月起，标记指数低于1%。通过频繁重复的脉冲标记和双重标记确定的生长分数，在19小时龄时约为40%，6周龄时约为8%，18月龄时低至1%或2%。通过双重标记和标记有丝分裂技术确定细胞周期各时相，结果显示S期、G2期和M期相对恒定。随着年龄增长，G1期延长。根据放射自显影结果，头部唾液腺可归类为稳定组织。
