Porst H
Z Gesamte Inn Med. 1983 Apr 15;38(8):30-2.
After the detection of a non-A/non-B-associated antigen/antibody system--identity with the system of Shirachi and co-workers--we analysed clinical and paraclinical data of 106 women after application of contaminated anti-D-immunoglobulin. Of 106 infected female patients 84 fell ill manifest, 22 cases showed typical prodromi of hepatitis. The incubation time could exactly be calculated with 55 days (+/- s = 11). Apart from the parenteral the non-parenteral possibility of transmission could be proved. Remarkable are 50% of chronic cases three years after infection. As favourable markers of prognosis juvenile age, appearance of prodromi and clinical symptoms as well as signs of cholestasis are to be mentioned.
在检测到一种与非甲非乙型肝炎相关的抗原/抗体系统(与Shirachi及其同事的系统相同)后,我们分析了106名使用受污染抗-D免疫球蛋白后的女性的临床和辅助临床数据。在106名受感染的女性患者中,84名出现明显症状,22例表现出典型的肝炎前驱症状。潜伏期可精确计算为55天(±标准差 = 11天)。除了经肠道外传播,非经肠道传播的可能性也得到了证实。值得注意的是,感染三年后有50%的慢性病例。作为预后的有利指标,可提及的有青少年年龄、前驱症状和临床症状的出现以及胆汁淤积的体征。