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[丙型病毒性肝炎作为非甲非乙型肝炎的一种免疫和临床定义形式。对该疾病的诊断、临床方面、辅助临床方面、病程、预后及预防的贡献]

[Virus hepatitis C as an immunologically and clinically defined form of non-A, non-B hepatitis. A contribution to the diagnosis, clinical aspects, paraclinical aspects, course, prognosis and prevention of this disease].

作者信息

Porst H

出版信息

Z Gesamte Inn Med. 1983 Apr 15;38(8):30-2.

PMID:6408816
Abstract

After the detection of a non-A/non-B-associated antigen/antibody system--identity with the system of Shirachi and co-workers--we analysed clinical and paraclinical data of 106 women after application of contaminated anti-D-immunoglobulin. Of 106 infected female patients 84 fell ill manifest, 22 cases showed typical prodromi of hepatitis. The incubation time could exactly be calculated with 55 days (+/- s = 11). Apart from the parenteral the non-parenteral possibility of transmission could be proved. Remarkable are 50% of chronic cases three years after infection. As favourable markers of prognosis juvenile age, appearance of prodromi and clinical symptoms as well as signs of cholestasis are to be mentioned.

摘要

在检测到一种与非甲非乙型肝炎相关的抗原/抗体系统(与Shirachi及其同事的系统相同)后,我们分析了106名使用受污染抗-D免疫球蛋白后的女性的临床和辅助临床数据。在106名受感染的女性患者中,84名出现明显症状,22例表现出典型的肝炎前驱症状。潜伏期可精确计算为55天(±标准差 = 11天)。除了经肠道外传播,非经肠道传播的可能性也得到了证实。值得注意的是,感染三年后有50%的慢性病例。作为预后的有利指标,可提及的有青少年年龄、前驱症状和临床症状的出现以及胆汁淤积的体征。

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