[Control of follicle maturation by estrogen determination in the serum and urine during treatment with gonadotropins].

Determinations of estrogen concentration in urine or serum for estimation of follicle maturity is a precondition for treatment with gonadotropines. -- Both methods determination are retrospectively compared in 22 cases. Only the RIA-method of 17 beta-estradiol determination is capable to recognize an overstimulation with a high rate of reliability, because the evidence of total estrogens in urine lags behind. Clinical tests such as Insler-score don't indicate chemical overstimulation.