Wolfe B M, Beer W H, Hayashi J T, Halsted C H, Cannon R A, Cox K L
Am J Surg. 1983 Jul;146(1):7-14. doi: 10.1016/0002-9610(83)90251-9.
Twenty-nine patients underwent courses of home parenteral nutrition therapy ranging from 1.5 to 52 months (mean 14.5 months). The primary diagnoses responsible for the requirement of home parenteral nutrition were radiation enteritis in seven patients, short bowel syndrome secondary to resection in seven, Crohn's disease in two, malabsorption states in six, and other reasons in seven. Seventeen patients (57 percent) had at least one complication. Nine patients had intravenous catheter complications and nine had metabolic complications. Nine patients have died, 11 have been successfully weaned from home parenteral nutrition, and 9 continue to receive home parenteral nutrition. Home parenteral nutrition is useful in a variety of catastrophic clinical situations, including preparation for subsequent operative therapy, temporary malabsorption, and permanent disability of the gastrointestinal tract. Complications are frequent and may be life-threatening.
29例患者接受了为期1.5至52个月(平均14.5个月)的家庭肠外营养治疗。需要家庭肠外营养的主要诊断包括:7例放射性肠炎、7例因切除导致的短肠综合征、2例克罗恩病、6例吸收不良状态以及7例其他原因。17例患者(57%)至少出现了一种并发症。9例患者出现静脉导管并发症,9例出现代谢并发症。9例患者死亡,11例已成功停用家庭肠外营养,9例继续接受家庭肠外营养。家庭肠外营养在多种灾难性临床情况中有用,包括为后续手术治疗做准备、暂时性吸收不良以及胃肠道永久性残疾。并发症很常见,可能危及生命。