Carter M L
Br Med J (Clin Res Ed). 1983 Jul 23;287(6387):247-8. doi: 10.1136/bmj.287.6387.247.
Four cases of severe bradycardia developed during surgery in patients given the neuromuscular blocking agent atracurium as part of the anaesthesia. In all cases sinus rhythm was restored by giving intravenous atropine. It is recommended that in all operations in which vagal stimulation is expected patients should be given atropine as part of the premedication or induction sequence and should undergo full electrocardiographic monitoring during surgery.
在麻醉过程中接受神经肌肉阻滞剂阿曲库铵的患者中,有4例在手术期间出现严重心动过缓。所有病例通过静脉注射阿托品恢复窦性心律。建议在所有预计会有迷走神经刺激的手术中,患者应在术前用药或诱导过程中给予阿托品,并在手术期间进行全面的心电图监测。