Davis K P, Maciulla G J, Yannone M E, Gooch G T, Lox C D, Whetstone M R
Obstet Gynecol. 1983 Sep;62(3):388-92. doi: 10.1097/00006250-198309000-00025.
A practical and accurate method of determining ovulation using cervical mucus is described. Ovulatory cycles from 32 healthy women were assessed using hormonal and nonhormonal methods. Cervical mucus extractable immunoglobulins were assayed for the complete cycles of nine women and randomly collected from 23 additional women with normal cycles. All normal ovulatory women showed a minimum concentration present at midcycle when optimum conditions for fertilization existed. Using newer laser nephelometry techniques, the content of extractable immunoglobulin G and immunoglobulin A per sample weight confirmed the cyclic nature of the concentration of immunoglobulin in cervical mucus, and correlated well with previously defined biophysical properties of cervical mucus. Nephelometry proved to be rapid, accurate, and an inexpensive technique for determining ovulation and has potential for clinical use.
本文描述了一种利用宫颈黏液确定排卵的实用且准确的方法。采用激素和非激素方法对32名健康女性的排卵周期进行了评估。对9名女性的整个周期测定了宫颈黏液可提取免疫球蛋白，并从另外23名月经周期正常的女性中随机采集样本。所有正常排卵的女性在排卵期中期，即存在最佳受精条件时，免疫球蛋白浓度最低。使用更新的激光散射比浊法技术，每个样本重量中可提取免疫球蛋白G和免疫球蛋白A的含量证实了宫颈黏液中免疫球蛋白浓度的周期性变化，并且与先前确定的宫颈黏液生物物理特性密切相关。散射比浊法被证明是一种快速、准确且廉价的确定排卵的技术，具有临床应用潜力。
