Debrun G M, Davis K R, Hochberg F H
AJNR Am J Neuroradiol. 1983 May-Jun;4(3):399-400.
Carmustine (BCNU) has been used extensively to treat glioblastomas by injection through a catheter placed in the cervical internal carotid artery. The technique causes severe pain to the eye and has resulted in ipsilateral blindness. The use of a latex calibrated-leak balloon positioned above the ophthalmic artery in the internal carotid artery or in one of its branches appears to circumvent the ocular complications mentioned. At an infusion rate at 125 ml/hr the balloon does not inflate and does not occlude the artery. This new technique has been used to treat 10 patients without complications.
卡莫司汀(BCNU)已被广泛用于通过置于颈内动脉的导管注射来治疗胶质母细胞瘤。该技术会给眼睛带来剧痛,并导致同侧失明。在颈内动脉或其分支之一中,使用置于眼动脉上方的乳胶校准泄漏球囊似乎可以避免上述眼部并发症。以125毫升/小时的输注速度时,球囊不会膨胀,也不会阻塞动脉。这项新技术已用于治疗10名患者,无并发症发生。