Glaubitt D, Haubrich J, Cordoni-Voutsas M
AJNR Am J Neuroradiol. 1983 May-Jun;4(3):560-3.
In an attempt to improve the diagnosis and to assess the intensity of intermittent cerebrospinal fluid rhinorrhea, indium-111 uptake by nasal pledgets during prolonged cisternography using 111In-DTPA was determined. In 12 patients having suspected cerebrospinal fluid rhinorrhea, cisternograms with calculation of counts/pixel in regions of interest were obtained, blood samples drawn, and nasal pledgets placed several times during 48 or 72 hr after lumbar intrathecal administration of 111In-DTPA. In three patients intermittent cerebrospinal fluid rhinorrhea was thus revealed; study by computed tomography was negative in each case. This procedure of extended radionuclide cisternography helped to detect, localize, and quantify intermittent cerebrospinal fluid rhinorrhea so that therapeutic decisions were facilitated and surgical intervention was minimized.
为了改进间歇性脑脊液鼻漏的诊断并评估其强度，我们测定了在使用铟-111二乙三胺五乙酸（111In-DTPA）进行长时间脑池造影期间鼻棉塞对铟-111的摄取情况。对12例疑似脑脊液鼻漏的患者，在经腰椎鞘内注射111In-DTPA后的48或72小时内，多次进行脑池造影，计算感兴趣区域的计数/像素，采集血样并放置鼻棉塞。由此发现了3例间歇性脑脊液鼻漏患者；计算机断层扫描检查在每种情况下均为阴性。这种延长的放射性核素脑池造影程序有助于检测、定位和量化间歇性脑脊液鼻漏，从而便于做出治疗决策并尽量减少手术干预。
