Manning J T, Ordonez N G, Barton J H
Arch Pathol Lab Med. 1983 Sep;107(9):456-8.
A 72-year-old woman was found at autopsy to have hepatic angiosarcoma approximately 30 years after systemic thorium oxide (Thorotrast) injection. Intracytoplasmic localization of factor VIII-related antigen was demonstrated by an immunoperoxidase method, confirming the endothelial cell origin of the tumor.
一名72岁女性在尸检时发现,在全身注射氧化钍(钍胶体)约30年后发生了肝血管肉瘤。通过免疫过氧化物酶法证实了肿瘤细胞内因子VIII相关抗原的定位,从而确认了该肿瘤的内皮细胞起源。