患病和正常老年人的甲状旁腺激素及25-羟维生素D浓度

Parathyroid hormone and 25-hydroxyvitamin D concentrations in sick and normal elderly people.

作者信息

Petersen M M, Briggs R S, Ashby M A, Reid R I, Hall M R, Wood P J, Clayton B E

出版信息

Br Med J (Clin Res Ed). 1983 Aug 20;287(6391):521-3. doi: 10.1136/bmj.287.6391.521.

DOI:10.1136/bmj.287.6391.521

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1548439/

Abstract

Serum 25-hydroxyvitamin D and immunoreactive parathyroid hormone concentrations were measured in normal elderly subjects living at home and in sick elderly patients in hospital. Normal old people tended to have high 25-hydroxyvitamin D and low parathyroid hormone concentrations; in the sick elderly this pattern was reversed. The raised serum parathyroid hormone concentrations in the sick elderly were not due to poor renal function and may have been a response to vitamin D deficiency. A high serum parathyroid hormone concentration in an elderly patient must be interpreted in the light of the patient's general health and nutritional state. Caution is needed in diagnosing primary hyperparathyroidism in this age group.

摘要

对居家的正常老年人和住院的患病老年人测定了血清25-羟维生素D和免疫反应性甲状旁腺激素浓度。正常老年人往往25-羟维生素D浓度高而甲状旁腺激素浓度低；在患病老年人中这种模式则相反。患病老年人血清甲状旁腺激素浓度升高并非由于肾功能不佳，可能是对维生素D缺乏的一种反应。老年患者血清甲状旁腺激素浓度高必须结合患者的总体健康状况和营养状况来解读。在这个年龄组诊断原发性甲状旁腺功能亢进时需要谨慎。

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