L-赖氨酸与甲醛之间的自发Nε-甲基化和Nε-甲酰化反应受到L-抗坏血酸的抑制。
Spontaneous N epsilon-methylation and N epsilon-formylation reactions between L-lysine and formaldehyde inhibited by L-ascorbic acid.
作者信息
Trézl L, Rusznák I, Tyihák E, Szarvas T, Szende B
出版信息
Biochem J. 1983 Aug 15;214(2):289-92. doi: 10.1042/bj2140289.
Abstract
For the inhibition of spontaneous N epsilon-methylation and N epsilon-formylation reactions between L-lysine and formaldehyde, L-ascorbic acid proved to be most suitable. The inhibition was not complete unless the molar concentration of ascorbic acid exceeded that of formaldehyde. T.l.c., potentiometric titration, n.m.r. spectroscopy and radiometric analysis were applied in the study of the inhibition process. Formaldehyde was reduced by L-ascorbic acid to ethylene glycol.
摘要
对于抑制L-赖氨酸与甲醛之间自发的Nε-甲基化和Nε-甲酰化反应，L-抗坏血酸被证明是最合适的。除非抗坏血酸的摩尔浓度超过甲醛的摩尔浓度，否则抑制作用并不完全。薄层色谱法、电位滴定法、核磁共振光谱法和放射性分析被用于抑制过程的研究。L-抗坏血酸将甲醛还原为乙二醇。
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