Cohen R J
Hosp Pract (Off Ed). 1983 Oct;18(10):199-205. doi: 10.1080/21548331.1983.11702670.
Therapeutic bloodletting dates back to ancient times. With the development of sophisticated in vivo cell separators, it has become an established and effective modality in the treatment of a number of hematologic-oncologic diseases. Apheresis must, however, be used with discrimination--only when more conservative measures have proved inadequate.
