两种双功能试剂作为甲醛甲酚替代品的生化研究。
A biochemical study of two bifunctional reagents as alternatives to formocresol.
作者信息
Ranly D M, Lazzari E P
出版信息
J Dent Res. 1983 Oct;62(10):1054-7. doi: 10.1177/00220345830620100901.
PMID:6413564
Abstract
Two bifunctional reagents, glutaraldehyde and dimethylsuberimidate, were compared to formaldehyde with respect to fixation and modification of protein. Glutaraldehyde proved the superior fixative based on cross-linking and enzyme degradation assays. An immunoprecipitation assay suggests that the reaction products of glutaraldehyde may have altered antigenicity.
摘要
将两种双功能试剂戊二醛和亚胺基二甲酯与甲醛在蛋白质固定和修饰方面进行了比较。基于交联和酶降解试验，戊二醛被证明是更优的固定剂。免疫沉淀试验表明，戊二醛的反应产物可能改变了抗原性。
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