Fell G S
J Inherit Metab Dis. 1983;6 Suppl 1:5-8. doi: 10.1007/BF01811316.
Trace elements levels in tissues show changes in various diseases including inborn errors of metabolism. Such changes may be primary or secondary due to stress or diseases of the liver and gastrointestinal tract. Measurement of trace elements in these cases may be essential both for diagnostic and therapeutic purposes. Trace element measurements can also be useful in other areas of clinical interest including nutrition, toxicity and therapy with inorganic pharmaceutical agents. The available techniques for measuring trace elements in tissues are summarized and the various problems of each are discussed.
组织中的微量元素水平在包括先天性代谢缺陷在内的各种疾病中会发生变化。由于应激或肝脏及胃肠道疾病，这种变化可能是原发性的或继发性的。在这些情况下，测量微量元素对于诊断和治疗目的可能都是必不可少的。微量元素测量在临床关注的其他领域也可能有用，包括营养、毒性以及无机药物治疗。本文总结了用于测量组织中微量元素的现有技术，并讨论了每种技术的各种问题。
