Hubert P, Mselati J C, Chassevent J, Cloup M
Arch Fr Pediatr. 1983 Jun-Jul;40(6):461-4.
Forty children with severe asthma were admitted to an intensive care unit from 1970 to 1981. Criteria of severity were alteration of consciousness, circulatory failure, hypercarbia greater than 7 KPa and paradoxical pulse greater than 35 mmHg persisting in spite of correct treatment. Some therapeutic measures (oxygen, corticosteroids, antibiotics, hydratation) were not modified during this period. On the contrary, bronchodilators, used at a higher dose since June 1980, were very effective on bronchospasm without side effects, making controlled ventilation unnecessary. These results seem to be very encouraging but have to be confirmed.
1970年至1981年期间,40名重症哮喘患儿被收治入重症监护病房。严重程度标准为意识改变、循环衰竭、二氧化碳潴留大于7千帕以及尽管经过正确治疗仍持续存在的奇脉大于35毫米汞柱。在此期间,一些治疗措施(氧气、皮质类固醇、抗生素、补液)未作改变。相反,自1980年6月起以更高剂量使用的支气管扩张剂对支气管痉挛非常有效且无副作用,使得无需进行控制通气。这些结果似乎非常令人鼓舞,但有待证实。