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情感障碍女性中促甲状腺激素对促甲状腺素刺激的反应与自杀行为的关系

Thyrotrophin response to thyreostimulin in affectively ill women relationship to suicidal behaviour.

作者信息

Linkowski P, Van Wettere J P, Kerkhofs M, Brauman H, Mendlewicz J

出版信息

Br J Psychiatry. 1983 Oct;143:401-5. doi: 10.1192/bjp.143.4.401.

DOI:10.1192/bjp.143.4.401
PMID:6414565
Abstract

Past history of suicidal behaviour was investigated in 51 depressed women (27 unipolar and 24 bipolar) in whom the TSH response to TRH was studied. Patients with a history of violent suicidal attempts were shown to have a reduced TSH response to TRH, compared to depressed patients with a history of non-violent suicidal attempts and depressed patients with no history of suicidal behaviour. A five-year follow-up study on these patients revealed that four patients who died from suicide had an absence of TSH response to TRH.

摘要

对51名患有抑郁症的女性(27名单相抑郁症患者和24名双相情感障碍患者)进行了自杀行为既往史调查,同时研究了她们对促甲状腺激素释放激素(TRH)的促甲状腺激素(TSH)反应。与有非暴力自杀未遂史的抑郁症患者和无自杀行为史的抑郁症患者相比,有暴力自杀未遂史的患者对TRH的TSH反应降低。对这些患者进行的一项为期五年的随访研究显示,四名死于自杀的患者对TRH无TSH反应。

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