急性白血病男性患者的性腺功能
Gonadal function in men treated for acute leukaemia.
作者信息
Waxman J, Terry Y, Rees L H, Lister T A
出版信息
Br Med J (Clin Res Ed). 1983 Oct 15;287(6399):1093-4. doi: 10.1136/bmj.287.6399.1093.
Abstract
Gonadal function was assessed in eight men in remission of leukaemia who had completed treatment eight months to eight years previously. All four men treated for acute myeloid leukaemia had normal sperm counts and motility, compared with only one of the four with acute lymphatic or undifferentiated leukaemia. Hormonal studies indicated that the sterility resulted from gonadal failure rather than pituitary dysfunction after cranial irradiation. These findings are important in the counselling of patients with leukaemia.
摘要
对8名白血病缓解期男性的性腺功能进行了评估，这些男性在8个月至8年前完成了治疗。与4名患有急性淋巴细胞或未分化白血病的男性中只有1人相比，所有4名接受急性髓细胞白血病治疗的男性精子计数和活力均正常。激素研究表明，不育是由于性腺功能衰竭而非头颅照射后的垂体功能障碍所致。这些发现对于白血病患者的咨询很重要。
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