Bauer G, Aichner F, Saltuari L
Eur Neurol. 1983;22(5):344-50. doi: 10.1159/000115581.
26 adult epileptic patients with diffuse slow spikes and waves and start of seizures after the age of 6 years were analyzed. The seizure spectrum encompasses generalized and focal seizures. The occurrence of several types of seizures is the rule. Epileptic drop attacks are most characteristic. Atonic, tonic and myoclonic features may be present in this type of seizure. Neurological and mental deficits are common. Compared with Lennox-Gastaut syndrome of children, the degree of intellectual impairment is relatively mild. As to the etiology a primary and a secondary group can be distinguished. Genetic predisposition seems to play a crucial role in the primary group.
对26例6岁后起病、伴有弥漫性慢棘波和慢波的成年癫痫患者进行了分析。癫痫发作谱包括全身性发作和局灶性发作。多种类型发作的出现是常见的。癫痫性跌倒发作最为典型。这种类型的发作可能伴有失张力、强直和肌阵挛特征。神经和精神缺陷很常见。与儿童Lennox-Gastaut综合征相比，智力损害程度相对较轻。关于病因，可以区分出原发性和继发性两组。遗传易感性在原发性组中似乎起着关键作用。
