Aster R H
Hosp Pract (Off Ed). 1983 Nov;18(11):187-90, 194-5, 198-9 passim. doi: 10.1080/21548331.1983.11702692.
The common denominator of this group of disorders is bleeding due to antibody-mediated platelet destruction. The variations in clinical manifestation--ranging from mild to fatal--reflect the diverse origins of the troublesome antibodies: transplacental, exogenous, and autogenous. Treatment--if necessary--may involve steroids, exchange transfusion, apheresis, or splenectomy.
这类病症的共同特征是由于抗体介导的血小板破坏而导致出血。临床表现的差异——从轻微到致命——反映了引发问题的抗体的不同来源:经胎盘的、外源性的和自身产生的。如有必要,治疗可能包括使用类固醇、换血疗法、血液成分单采术或脾切除术。