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甲状腺的同步发射和荧光扫描。

Simultaneous emission and fluorescent scanning of the thyroid.

作者信息

Patton J A, Brill A B

出版信息

J Nucl Med. 1978 May;19(5):464-9.

PMID:641567
Abstract

A comparison study of lithium-drifted silicon [Si(Li)] and high purity germanium (HpGe) was performed to explore the feasibility of replacing the current Si(Li) detector with the higher-efficiency HpGe detector. The improved efficiency of HpGe permits the use of collimators with higher resolution, which results in improved image quality over that achieved by the current Si(Li) system in use at Vanderbilt with an overall reduction in sensitivity of 29%. Since a 10 mm thick HpGe detector is about 75% efficient at 140 keV, the added advantage exists of simultaneously (a) imaging the stable-iodine distribution within the thyroid by x-ray fluorescence, and (b) the distribution of administered radiotracers such as [99mTc] pertechnetate. This comparison study shows that HpGe can compete with Si(Li) in overall detector efficiency, with the added benefits of better collimation to improve spatial resolution plus the simultaneous imaging of Tc-99m, all at the same equipment cost.

摘要

进行了锂漂移硅[Si(Li)]探测器和高纯锗(HpGe)探测器的对比研究,以探讨用更高效率的HpGe探测器取代现有Si(Li)探测器的可行性。HpGe探测器效率的提高使得能够使用具有更高分辨率的准直器,这将带来比范德堡大学目前使用的Si(Li)系统更好的图像质量,同时灵敏度整体降低29%。由于10毫米厚的HpGe探测器在140keV时效率约为75%,因此还具有额外的优势,即能够同时:(a) 通过X射线荧光成像甲状腺内的稳定碘分布;(b) 成像诸如高锝[99mTc]酸盐之类的放射性示踪剂的分布。这项对比研究表明,HpGe在整体探测器效率方面可与Si(Li)相媲美,并且具有更好的准直性以提高空间分辨率以及同时成像Tc-99m的额外优势,而设备成本相同。

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