Tamsen L, Axelsson O, Johansson S G
Gynecol Obstet Invest. 1983;16(5):253-60. doi: 10.1159/000299273.
Pregnancy-specific beta 1-glycoprotein (SP1) concentrations were measured by nephelometry in 133 serum samples from 74 women in their last trimester of pregnancy. All women carried one child but their pregnancies were complicated by pre-eclampsia, essential hypertension, diabetes mellitus or rhesus isoimmunization. Most of the women with pre-eclampsia or essential hypertension who gave birth to infants of normal weight had SP1 values evenly distributed within the reference range. Women with insulin-dependent diabetes mellitus who gave birth to infants to normal birth weight or large-for-date infants had SP1 levels well within the reference range and even showed a tendency to overrepresentation above the geometric mean. Women with rhesus isoimmunization all delivered infants of normal birth weight. Their SP1 values were near or above the geometric mean of the reference range. No special pattern of SP1 levels was observed in relation to the severity of the immunization.
采用散射比浊法测定了74名妊娠晚期妇女133份血清样本中妊娠特异性β1-糖蛋白（SP1）的浓度。所有妇女均为单胎妊娠，但她们的妊娠合并子痫前期、原发性高血压、糖尿病或恒河猴血型不合免疫。大多数子痫前期或原发性高血压且分娩出体重正常婴儿的妇女，其SP1值在参考范围内均匀分布。分娩出体重正常婴儿或大于胎龄儿的胰岛素依赖型糖尿病妇女，其SP1水平在参考范围内，甚至有高于几何平均数的趋势。恒河猴血型不合免疫的妇女均分娩出体重正常的婴儿。她们的SP1值接近或高于参考范围的几何平均数。未观察到与免疫严重程度相关的SP1水平特殊模式。
