Erwall C, Ejerblad S, Lindholm C E, Aberg T
Acta Otolaryngol. 1984 Jan-Feb;97(1-2):185-92. doi: 10.3109/00016488409130979.
A series of 48 patients with oesophageal perforations was reviewed retrospectively. Eighty-seven per cent of the perforations were iatrogenic. Twenty-four patients were treated conservatively; 3 of this group died. The other 24 patients were treated surgically and 4 of them died. Patients with alarming symptoms and/or a large perforation underwent operative treatment unless there were contra-indications. Retained foreign bodies after perforation, and malignancy in the perforation area, were considered as indications for operation. Conservative treatment was reserved for patients with minor tears combined with a less turbulent course. The interval between perforation and therapy was not of decisive importance for the mortality in our series. The clinical picture, which was dominated by chest pain, gave the earliest indication of perforation, while the responses of the sedimentation rate, temperature and white blood count occurred later and were less reliable diagnostic signs.
对48例食管穿孔患者进行了回顾性研究。87%的穿孔为医源性。24例患者接受保守治疗,其中3例死亡。另外24例患者接受手术治疗,其中4例死亡。有警示症状和/或大穿孔的患者,除非有禁忌证,均接受手术治疗。穿孔后残留异物以及穿孔部位的恶性肿瘤被视为手术指征。保守治疗适用于小撕裂且病情发展较平稳的患者。在我们的研究系列中,穿孔与治疗之间的间隔对死亡率并非起决定性作用。以胸痛为主的临床表现最早提示穿孔,而血沉、体温和白细胞计数的变化出现较晚,且作为诊断体征可靠性较低。