Hagiwara A, Takahashi T, Ueda T, Takeda M, Lee R, Mizuguchi N
Gan To Kagaku Ryoho. 1983 Dec;10(12):2558-64.
Small charcoal particles adsorbing Mitomycin C (MMC-CH) were used in the treatment of lymphnode metastasis of gastric cancer. Immediately after injection of MMC-CH into the gastric wall, lymph capillaries and regional lymphnodes were stained in black and the high concentration of MMC was delivered with charcoal particles. MMC-CH was injected preoperatively using endoscope into the gastric wall of 20 patients with gastric cancer. MMC-CH was observed in 70% of metastatic regional lymphnodes. Systemic side effect was not noted at all. Erosion and shallow ulcers were observed at the site of injection but no perforation occurred.
吸附丝裂霉素C的小炭颗粒（MMC-CH）被用于治疗胃癌淋巴结转移。将MMC-CH注入胃壁后，淋巴管和区域淋巴结立即被染成黑色，高浓度的丝裂霉素C随炭颗粒一同输送。术前通过内镜将MMC-CH注入20例胃癌患者的胃壁。在70%的转移区域淋巴结中观察到了MMC-CH。未观察到任何全身副作用。在注射部位观察到糜烂和浅溃疡，但未发生穿孔。
