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Effect of sinusoidal perfusion on galactose elimination kinetics in perfused rat liver.

作者信息

Keiding S, Chiarantini E

出版信息

J Pharmacol Exp Ther. 1978 May;205(2):465-70.

PMID:641841
Abstract
摘要

相似文献

1
Effect of sinusoidal perfusion on galactose elimination kinetics in perfused rat liver.正弦灌注对灌注大鼠肝脏中半乳糖消除动力学的影响。
J Pharmacol Exp Ther. 1978 May;205(2):465-70.
2
Effects of acute carbon tetrachloride intoxication on kinetics of galactose elimination by perfused rat livers.急性四氯化碳中毒对灌注大鼠肝脏半乳糖消除动力学的影响。
Scand J Clin Lab Invest. 1983 Apr;43(2):127-31.
3
Hepatic galactose elimination kinetics in the intact pig.完整猪肝脏中半乳糖清除动力学
Scand J Clin Lab Invest. 1982 May;42(3):253-9.
4
Mechanisms of lidocaine kinetics in the isolated perfused rat liver. II. Kinetics of steady state elimination.利多卡因在离体灌流大鼠肝脏中的动力学机制。II. 稳态消除动力学
Drug Metab Dispos. 1987 Jan-Feb;15(1):17-21.
5
Importance of flow and haematocrit for metabolic function of perfused rat liver.
Scand J Clin Lab Invest. 1980 Jun;40(4):355-9. doi: 10.3109/00365518009092655.
6
Michaelis-Menten kinetics of galactose elimination by the isolated perfused pig liver.离体灌注猪肝消除半乳糖的米氏动力学
Am J Physiol. 1976 May;230(5):1302-13. doi: 10.1152/ajplegacy.1976.230.5.1302.
7
Galactose elimination kinetics in perfused rat liver after two thirds hepatectomy.
Scand J Clin Lab Invest. 1984 Apr;44(2):155-8. doi: 10.3109/00365518409161397.
8
Discrimination between the venous equilibrium and sinusoidal models of hepatic drug elimination in the isolated perfused rat liver by perturbation of propranolol protein binding.通过普萘洛尔蛋白结合的扰动来区分离体灌注大鼠肝脏中肝药物消除的静脉平衡模型和窦状隙模型。
J Pharmacol Exp Ther. 1984 May;229(2):522-6.
9
Flow dependence of propranolol elimination in perfused rat liver.
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10
Urea excretion, galactose elimination, and aminopyrine disappearance during normal liver regeneration after partial hepatectomy. Comparison with other function tests reported.部分肝切除术后正常肝再生过程中的尿素排泄、半乳糖清除及氨基比林消失情况。与所报道的其他功能测试的比较。
J Lab Clin Med. 1984 Jul;104(1):24-34.

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A Complete Extension of Classical Hepatic Clearance Models Using Fractional Distribution Parameter f in Physiologically Based Pharmacokinetics.使用生理药代动力学中的分数分布参数 f 对经典肝脏清除模型进行全面扩展。
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Are There Any Experimental Perfusion Data that Preferentially Support the Dispersion and Parallel-Tube Models over the Well-Stirred Model of Organ Elimination?是否存在更倾向于支持分配和并行管模型而不是器官消除的完全混合模型的实验灌注数据？
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3
Hepatic uptake and metabolism of galactose can be quantified in vivo by 2-[18F]fluoro-2-deoxygalactose positron emission tomography.
半乳糖的肝脏摄取和代谢可通过2-[18F]氟-2-脱氧半乳糖正电子发射断层扫描在体内进行定量分析。
Am J Physiol Gastrointest Liver Physiol. 2008 Jul;295(1):G27-G36. doi: 10.1152/ajpgi.00004.2008. Epub 2008 May 15.
4
An understanding of flow- and diffusion-limited vs. carrier-mediated hepatic transport: a simulation study.流动和扩散限制与载体介导的肝脏转运的理解：一项模拟研究。
J Pharmacokinet Biopharm. 1995 Aug;23(4):347-78. doi: 10.1007/BF02353638.
5
An understanding of the role of enzyme localization of the liver on metabolite kinetics: a computer simulation.
J Pharmacokinet Biopharm. 1983 Oct;11(5):451-68. doi: 10.1007/BF01062205.
6
Theoretical considerations in the calculation of bioavailability of drugs exhibiting Michaelis-Menten elimination kinetics.具有米氏消除动力学特征的药物生物利用度计算中的理论考量
J Pharmacokinet Biopharm. 1984 Aug;12(4):437-50. doi: 10.1007/BF01062667.
7
Protein binding and hepatic clearance: discrimination between models of hepatic clearance with diazepam, a drug of high intrinsic clearance, in the isolated perfused rat liver preparation.蛋白结合与肝脏清除率：在离体灌注大鼠肝脏制备中，用高内在清除率药物地西泮区分肝脏清除率模型。
J Pharmacokinet Biopharm. 1984 Apr;12(2):129-47. doi: 10.1007/BF01059274.
8
First-pass elimination. Basic concepts and clinical consequences.首过消除。基本概念及临床后果。
Clin Pharmacokinet. 1984 Jan-Feb;9(1):1-25. doi: 10.2165/00003088-198409010-00001.
9
A nonlinear physiologic pharmacokinetic model: I. Steady-state.一种非线性生理药代动力学模型：I. 稳态
J Pharmacokinet Biopharm. 1985 Feb;13(1):73-92. doi: 10.1007/BF01073657.
10
A dispersion model of hepatic elimination: 2. Steady-state considerations--influence of hepatic blood flow, binding within blood, and hepatocellular enzyme activity.肝脏消除的弥散模型：2. 稳态考量——肝血流量、血液内结合以及肝细胞酶活性的影响
J Pharmacokinet Biopharm. 1986 Jun;14(3):261-88. doi: 10.1007/BF01106707.