Børglum Jensen S, Jacobsen P, Rotne L, Enk C, Illum F
Int J Oral Surg. 1983 Aug;12(4):250-4. doi: 10.1016/s0300-9785(83)80050-7.
An 8-year-old female with DiGeorge syndrome was referred for dental treatment. Previous medical examination had disclosed heart and aortic arch malformations, hypoparathyroidism and an impaired cellular immune response. At dental examination, hypertelorism, a short philtrum, low-set malformed ears, a cleft palate and severe enamel hypoplasia were noted. The chronological distribution of enamel defects corresponded to the patients' age at known episodes of profound hypocalcemia occurring during treatment with vitamin D. Branchial dysembryogenesis should be considered in any case with dental changes related to hypoparathyroidism.
一名患有迪格奥尔格综合征的8岁女性被转诊接受牙科治疗。先前的医学检查发现有心脏和主动脉弓畸形、甲状旁腺功能减退以及细胞免疫反应受损。牙科检查时，发现两眼间距过宽、人中短、低位畸形耳、腭裂和严重的釉质发育不全。釉质缺陷的时间分布与患者在使用维生素D治疗期间发生严重低钙血症的已知发作时的年龄相符。对于任何伴有与甲状旁腺功能减退相关牙科变化的病例，都应考虑鳃弓发育异常。
