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抗血清与人类和恒河猴精子上的性类固醇及人促性腺激素的结合模式。

The binding patterns of antisera to sex steroids and human gonadotropins on human and rhesus monkey spermatozoa.

作者信息

Allag I S, Das R P, Roy S

出版信息

J Androl. 1983 Nov-Dec;4(6):415-20. doi: 10.1002/j.1939-4640.1983.tb00769.x.

DOI:10.1002/j.1939-4640.1983.tb00769.x
PMID:6418700
Abstract

The presence of different hormones on the surface of ejaculated spermatozoa was determined by immunofluorescence studies of the binding patterns of specific antisera to these hormones. There were striking similarities in the binding pattern of antisera to steroid hormones found on human and monkey spermatozoa. Assuming the intensity of fluorescence is proportional to the concentration of the hormone, concentrations of testosterone on the acrosomal and the postacrosomal regions were higher than levels of progesterone and estrogens. Spermatozoa with a "tapering head" had more hCG bound on the acrosomal and postacrosomal regions than spermatozoa with "normal head" (oval shaped). Correlating these findings to the functions of spermatozoa will require further studies.

摘要

通过对特定抗血清与这些激素的结合模式进行免疫荧光研究,确定了射出精子表面不同激素的存在情况。在人类和猴子精子上发现的抗血清与类固醇激素的结合模式存在显著相似性。假设荧光强度与激素浓度成正比,顶体和顶体后区域的睾酮浓度高于孕酮和雌激素水平。“头部逐渐变细”的精子在顶体和顶体后区域结合的人绒毛膜促性腺激素比“正常头部”(椭圆形)的精子更多。将这些发现与精子的功能相关联还需要进一步研究。

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