Ferenczy A
Am J Obstet Gynecol. 1984 Jan 1;148(1):9-12. doi: 10.1016/s0002-9378(84)80024-1.
The therapeutic effectiveness of the carbon dioxide laser was evaluated in 43 pregnant women with extensive urogenital and anal condylomas. All patients received one treatment and were followed up for an average of 9 months after delivery. Laser failures (persistent disease) and recurrences (new disease) were stratified according to the location of the lesions and the gestational age of the patients. The overall failure rate was 5%; 6% of the women with multiple sites involved had persistent disease but none of the lesions confined to the vulva persisted after laser treatment. The recurrence rate was 14%; 33% and 17% of the patients treated during the first and second trimesters, respectively, had recurrent disease irrespective of the areas involved. Recurrences were not observed in women treated during the third trimester of pregnancy. Laser vaporization of genital condylomas was not associated with perioperative or postoperative bleeding or infections. Laser therapy is an attractive means of treating urogenital and anal condylomas during pregnancy and is most effective near term.
对43例患有广泛泌尿生殖系统及肛周尖锐湿疣的孕妇评估了二氧化碳激光的治疗效果。所有患者均接受了一次治疗，并在产后平均随访9个月。根据病变部位和患者孕周对激光治疗失败（疾病持续存在）和复发（出现新疾病）情况进行了分层。总体失败率为5%；多个部位受累的女性中有6%疾病持续存在，但局限于外阴的病变经激光治疗后均未持续存在。复发率为14%；分别在孕早期和孕中期接受治疗的患者中，有33%和17%出现疾病复发，与受累部位无关。妊娠晚期接受治疗的女性未观察到复发情况。生殖器尖锐湿疣的激光汽化治疗与围手术期或术后出血或感染无关。激光治疗是孕期治疗泌尿生殖系统及肛周尖锐湿疣的一种有吸引力的方法，且在孕晚期最为有效。
