Saint-Pierre A, Martinez G, Milon H, Amiel M
Arch Mal Coeur Vaiss. 1983 Nov;76(11):1316-25.
The aim of this study to assess the predictive value of exercise stress testing (ET) compared with coronary angiography-left ventriculography (CLV) in 102 patients undergoing physical rehabilitation (PH) after myocardial infarction (MI). The ET was optimised in its performance by the PH and in its interpretation by the selection of the parameters according to the site of MI. In anterior MI, angina (30%) and ischemic ST depression outside the acute period (35%) had little predictive value of multivessel disease which was demonstrated in 40% of cases; on the other hand, ST elevation in the same area as MI (65%) had an 88% predictive value for severe LV impairment which was found in 66% of cases. In inferior MI, ischemic ST depression (75%) more than angina (27%) was of greater predictive value (82%) for multivessel disease which was demonstrated in 59% of cases. The sensitivity was 97% and the specificity 64%; the LAD artery was diseased in 48% of cases. LV function was preserved in 63% of cases, but ET was not useful in the prediction of this parameter. In all cases of MI, the absence of ST changes predicted single vessel disease in 94%; ventricular arrhythmias (5%) stopped the patients reaching a discriminative exercise level but indicated poor LV function. The extreme values of heart rate and double product improved the correlations between ET and CLV. Therefore, ET may provide some of the information of CLV before the usual evolutive criteria and may help avoid this investigation in patients with favourable results, especially with inferior infarction. Although it has no absolute value, systematic ET is justified after MI as it enables the most severe cases to be distinguished from the most benign.
本研究旨在评估运动应激试验(ET)与冠状动脉造影-左心室造影(CLV)相比,对102例心肌梗死(MI)后接受心脏康复(PH)患者的预测价值。通过心脏康复优化ET的操作,并根据MI部位选择参数来优化其解读。在前壁MI中,心绞痛(30%)和急性期外的缺血性ST段压低(35%)对多支血管病变的预测价值不大,40%的病例显示存在多支血管病变;另一方面,与MI相同区域的ST段抬高(65%)对严重左心室功能损害的预测价值为88%,66%的病例存在严重左心室功能损害。在下壁MI中,缺血性ST段压低(75%)比心绞痛(27%)对多支血管病变的预测价值更大(82%),59%的病例显示存在多支血管病变。敏感性为97%,特异性为64%;48%的病例左前降支动脉病变。63%的病例左心室功能得以保留,但ET对该参数的预测并无帮助。在所有MI病例中,ST段无变化对单支血管病变的预测率为94%;室性心律失常(5%)使患者无法达到有鉴别意义的运动水平,但提示左心室功能较差。心率和双乘积的极值改善了ET与CLV之间的相关性。因此,ET可能在常规演变标准之前提供一些CLV的信息,并有助于避免对结果良好的患者进行该项检查,尤其是下壁梗死患者。尽管ET没有绝对价值,但MI后进行系统性ET是合理的,因为它能够区分最严重的病例和最良性的病例。