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The relationship between nutritional adequacy and brain myelin accumulation: a comparison of varying degrees of well fed and undernourished rats.

作者信息

Fuller G N, Johnston D A, Wiggins R C

出版信息

Brain Res. 1984 Jan 2;290(1):195-8. doi: 10.1016/0006-8993(84)90755-8.

DOI:10.1016/0006-8993(84)90755-8
PMID:6419986
Abstract

Rats undernourished through 17 days of age to produce mild weight lag (less than 20%) had either the same amount, or slightly more myelin than well fed controls. Schedules of undernourishment producing approximately 30, 40 and 50% body weight lags produced corresponding rank-ordered myelin deficits of 25, 55 and 60%, respectively. Brain growth was relatively spared in all cases, never exceeding a deficit of 10%. Absolute myelin deficits did not recover following nutritional rehabilitation, although myelin continued to increase in both normal and all test populations.

摘要

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