Kulshrestha S K, Arora N
Toxicol Lett. 1984 Jan;20(1):93-8. doi: 10.1016/0378-4274(84)90189-9.
Impairments induced by sublethal doses of two pesticides Carbaryl and Endosulfan have been studied on the ovaries of a freshwater teleost Channa striatus by exposing the fish for a period of 2 to 30 days during the spawning season. The pesticide exposure produced reduction in the number of oocytes, reduction in size and deformity in different stages of oocytes, damage to yolk vesicles in maturing and mature oocytes, increase in the number of atretic oocytes, development of interfollicular spaces, increase in the connective tissue of tunica albuginea, dilation of blood vessels and reduction in the gonadosomatic index. The histopathological effects were dependent on the dose, duration of exposure, and the type of pesticide. Sublethal doses of Endosulfan were more toxic than those of Carbaryl.
在产卵季节,通过将淡水硬骨鱼条纹鳢暴露2至30天,研究了两种农药西维因和硫丹的亚致死剂量对其卵巢造成的损害。农药暴露导致卵母细胞数量减少、卵母细胞不同阶段大小减小和畸形、成熟和成熟卵母细胞中的卵黄囊受损、闭锁卵母细胞数量增加、卵泡间隙形成、白膜结缔组织增加、血管扩张以及性腺指数降低。组织病理学效应取决于剂量、暴露持续时间和农药类型。硫丹的亚致死剂量比西维因的毒性更大。