Reinold E
Wien Med Wochenschr. 1983 Dec 31;133(23-24):610-3.
Before the general introduction of Rhesus-prophylaxis the frequency of morbus haemolyticus neonatorum was about 0.6%. In spite of the simple collection of "Rhesus-negative" mothers and the administration of the Rhesus-prophylaxis there are still some cases of morbus haemolyticus neonatorum; in our department 2 cases (or 0.11%) last year. The possible causes of non-successful Rhesus-prophylaxis are: immunisation during a previous abortion; immunisation during a previous delivery or a non-adequate blood-transfusion; in a previous delivery there was a macrotransfusion and therefore the doses of Rhesus-prophylaxis too small; the administration of Rhesus-prophylaxis was too late (later than 72 hours post partum); inadequate standardisation or storage of the drug; immunisation during the present pregnancy.
在普遍引入恒河猴因子预防措施之前，新生儿溶血病的发病率约为0.6%。尽管简单收集“恒河猴因子阴性”母亲并实施恒河猴因子预防措施，但仍有一些新生儿溶血病病例；去年在我们科室有2例（或0.11%）。恒河猴因子预防措施未成功的可能原因有：既往流产时发生免疫；既往分娩或输血不当时发生免疫；既往分娩时有大量输血，因此恒河猴因子预防剂量过小；恒河猴因子预防措施给药过晚（产后72小时后）；药物标准化或储存不当；本次妊娠期间发生免疫。
