接受强化输血治疗的纯合子β地中海贫血患者血清、毛发和尿液中的锌水平。

Zinc levels of serum, hair and urine in homozygous beta-thalassemic subjects under hypertransfusional treatment.

作者信息

Rea F, Perrone L, Mastrobuono A, Toscano G, D'Amico M

出版信息

Acta Haematol. 1984;71(2):139-42. doi: 10.1159/000206574.

DOI:10.1159/000206574

Abstract

The concentration of zinc in serum, hair and urine has been examined in 92 homozygous beta-thalassemic and 81 control subjects. The results were not statistically different in the subjects of each group studied (thalassemic and control persons of different ages: 1-12, 12-18, and 18-35 years). In the thalassemic children no statistically significant differences were observed between those normally growing and those with impaired growth. The authors hypothesize that hypertransfusional treatment prevents zinc deficiency in the thalassemic patients.

摘要

对92名纯合子β地中海贫血患者和81名对照者的血清、头发和尿液中的锌浓度进行了检测。在每组研究对象（不同年龄的地中海贫血患者和对照者：1 - 12岁、12 - 18岁和18 - 35岁）中，结果无统计学差异。在地中海贫血儿童中，正常生长的儿童和生长发育受损的儿童之间未观察到统计学上的显著差异。作者推测，强化输血治疗可预防地中海贫血患者出现锌缺乏。